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Kinesin inhibitor, K 858, Purity ≥98%
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Cat. No.: X24-08-YM326

Kinesin inhibitor, K 858, Purity ≥98%

Synonym: 72926-24-0; K-858; K858; N-(4-Acetyl-5-methyl-5-phenyl-1,3,4-thiadiazol-2-yl)acetamide

  • MDL: MFCD00181155
  • CAS Number: 72926-24-0
  • Compound CID: 2930014
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
MSDS
Properties
Description
K 858, soluble in DMSO and ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting kinesin. It targets the Eg5.
Molecular Weight
277.34
Molecular Formula
C13H15N3O2S
Targets
Eg5: 1.3 μM (IC50)
Form
Lyophilized powder
Purity
≥98%
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 53 mg/mL (191.1 mM); Water: insoluble; Ethanol: 4 mg/mL (14.42 mM)
Applications
K 858 is a cytoskeletal signaling inhibitor that plays a key role in disrupting mitotic spindle formation, which can lead to cancer cell death.
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