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LRRK2 inhibitor, GSK2578215A, Purity ≥98%
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Cat. No.: X24-09-YM698

LRRK2 inhibitor, GSK2578215A, Purity ≥98%

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Synonym: 1285515-21-0; GSK-2578215A; GSK 2578215A; 5-(2-Fluoropyridin-4-yl)-2-phenylmethoxy-N-pyridin-3-ylbenzamide; LRRK2 inhibitor

  • MDL: MFCD22665702
  • CAS Number: 1285515-21-0
  • Compound CID: 68107965
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
GSK2578215A, soluble in DMSO and insoluble in water and ethanol, is an effective autophagy signaling inhibitor, that has the ability to prevent the pathway of autophagy signaling by inhibiting LRRK2. The molecular weight of the compound is 399.42, and its molecular formula is C24H18FN3O2. It targets the LRRK2 (G2019S) and LRRK2 (WT).
Molecular Weight
399.42
Molecular Formula
C24H18FN3O2
Targets
LRRK2 (G2019S)
Form
Lyophilized powder
Purity
≥98%
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO (warmed): 73 mg/mL (182.76 mM); Water: insoluble; Ethanol: insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
GSK2578215A can be used for its effects on Parkinson’s disease and other conditions related to LRRK2 dysregulation.
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