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LXS196
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Cat. No.: X23-12-YM059

LXS196

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Synonym: 1874276-76-2; Darovasertib

  • CAS Number: 1874276-76-2
  • PubChem CID: 118873253
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Product Size
2 mg; 5 mg; 10 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
LXS196, soluble in DMSO and ethanol and insoluble in water, blocks the function of Smad proteins in the TGF-β signaling pathway. It targets GSK3β, PKCα, and PKCθ.
Molecular Weight
472.47
Molecular Formula
C22H23F3N8O
Targets
GSK3β: 3.1 μM; PKCα: 1.9 nM; PKCθ: 0.4 nM
Form
Lyophilized powder
Purity
>98%
Solubility
DMSO: 20 mg/mL (42.33 mM); Water: insoluble; Ethanol: 5 mg/mL (10.58 mM)
Applications
LXS196 can be used as a novel approach for managing various types of pain, including neuropathic pain and inflammatory pain.
Publications
Publications (0)

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