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Microtubule/Tubulin inhibitor, CK-636, Purity ≥98%

Cat. No.: X24-08-YM230

Microtubule/Tubulin inhibitor, CK-636, Purity ≥98%

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Synonym: 442632-72-6; CK636; CK 636; N-[2-(2-Methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide; N-[2-(2-Methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide

  • MDL: MFCD03036245
  • CAS Number: 442632-72-6
  • Compound CID: 588963
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
CK-636, soluble in DMSO and ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting microtubule/tubulin. It targets the Bovine Arp2/3 complex, fission yeast Arp2/3 complex, and human Arp2/3 complex.
Molecular Weight
284.09833
Molecular Formula
C16H16N2OS
Targets
Bovine Arp2/3 complex: 32 μM; Fission yeast Arp2/3 complex: 24 μM; Human Arp2/3 complex: 4 μM
Form
Lyophilized powder
Purity
≥98%
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 52 mg/mL (182.85 mM); Water: insoluble; Ethanol: 46 mg/mL
Applications
CK-636 is a cytoskeletal signaling inhibitor that plays a key role in reducing the formation of lamellipodia, leading to a decrease in migration speed.
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Blood Group and Lewis Antigen
Blood group A trisaccharide (Cat#: XCO0060Q) Blood group B trisaccharide (Cat#: XCO0068Q) Blood group H disaccharide (Cat#: XCO0074Q) Lewis A trisaccharide (Cat#: XCO0079Q) 3'-Sulfated lewis A (Cat#: XCO0080Q) Lewis B tetrasaccharide (Cat#: XCO0083Q) Lewis X trisaccharide (Cat#: XCO0085Q) Lewis Y tetrasaccharide (Cat#: XCO0088Q)
Human Milk Oligosaccharides (HMOs)
Lacto-N-biose (Cat#: XCO0089Q) 2'-Fucosyllactose (Cat#: XCO0091Q) 3-Fucosyllactose (Cat#: XCO0092Q) Lactodifucotetraose (Cat#: XCO0093Q) Lacto-N-triose I (Cat#: XCO0094Q) 3'-Sialyllactose sodium salt (Cat#: XCO0096Q) 6'-Sialyllactose sodium salt (Cat#: XCO0098Q) 3'-Sialyl-3-fucosyllactose (Cat#: XCO0100Q)
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Heparin amine, MW 27 kDa (Cat#: X22-09-ZQ478) FITC-heparin, MW 27 kDa (Cat#: X22-09-ZQ480) TRITC-heparin, MW 27 kDa (Cat#: X22-09-ZQ481) Biotin-heparin-FITC, MW 18 kDa (Cat#: X22-09-ZQ482) Chondroitin sulfate (dp4) (Cat#: X22-11-ZQ598) Dermatan sulfate (dp12) (Cat#: X22-11-ZQ611) Heparin disaccharide I-A (Cat#: X22-11-ZQ662) Chondroitine sulfate (Cat#: X23-04-XQ1118)
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