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Cat. No.: X24-08-YM230

Microtubule/Tubulin inhibitor, CK-636, Purity ≥98%

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Synonym: 442632-72-6; CK636; CK 636; N-[2-(2-Methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide; N-[2-(2-Methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide

  • MDL: MFCD03036245
  • CAS Number: 442632-72-6
  • Compound CID: 588963
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
CK-636, soluble in DMSO and ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting microtubule/tubulin. It targets the Bovine Arp2/3 complex, fission yeast Arp2/3 complex, and human Arp2/3 complex.
Molecular Weight
284.09833
Molecular Formula
C16H16N2OS
Targets
Bovine Arp2/3 complex: 32 μM; Fission yeast Arp2/3 complex: 24 μM; Human Arp2/3 complex: 4 μM
Form
Lyophilized powder
Purity
≥98%
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 52 mg/mL (182.85 mM); Water: insoluble; Ethanol: 46 mg/mL
Applications
CK-636 is a cytoskeletal signaling inhibitor that plays a key role in reducing the formation of lamellipodia, leading to a decrease in migration speed.
Publications
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