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Microtubule/Tubulin inhibitor, Monomethyl auristatin E, Purity ≥98%
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Cat. No.: X24-08-YM212

Microtubule/Tubulin inhibitor, Monomethyl auristatin E, Purity ≥98%

Synonym: 474645-27-7; Monomethylauristatin E; MMAE; Monomethyl auristatin E (GMP); SGD-1010; (2S)-N-[(2S)-1-[[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-3-[[(1S,2R)-1-Hydroxy-1-phenylpropan-2-yl]amino]-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-methylamino]-3-methyl-1-oxobutan-2-yl]-3-methyl-2-(methylamino)butanamide

  • MDL: MFCD22124498
  • CAS Number: 474645-27-7
  • Compound CID: 11542188
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
MSDS
Properties
Description
Monomethyl auristatin E, soluble in DMSO and ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting microtubule/tubulin.
Molecular Weight
717.98
Molecular Formula
C39H67N5O7
Form
Lyophilized powder
Purity
≥98%
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 93 mg/mL (129.52 mM); Water: insoluble; Ethanol: 93 mg/mL (129.52 mM)
Applications
Monomethyl auristatin E is a cytoskeletal signaling inhibitor that can be used for its ability to deliver cytotoxic drugs directly to cancer cells, minimizing off-target effects and improving therapeutic efficacy.
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