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Microtubule/Tubulin inhibitor, Combretastatin A4, Purity ≥98%

Cat. No.: X24-08-YM224

Microtubule/Tubulin inhibitor, Combretastatin A4, Purity ≥98%

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Synonym: 117048-59-6; CRC 87-09; NSC 817373; 2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol

  • MDL: MFCD03453309
  • CAS Number: 117048-59-6
  • Compound CID: 5351344
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Combretastatin A4, soluble in DMSO and warmed ethanol and insoluble in water, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting microtubule/tubulin.
Molecular Weight
316.35
Molecular Formula
C18H20O5
Form
Lyophilized powder
Purity
≥98%
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 58 mg/mL (183.34 mM); Water: insoluble; Ethanol (warmed): 31 mg/mL (97.99 mM); In vivo: 5% DMSO + 50% PEG 300 + ddH2O, 28 mg/mL
Applications
Combretastatin A4 is a cytoskeletal signaling inhibitor that plays a key role in disrupting the blood supply to tumors.
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Blood Group and Lewis Antigen
Blood group A trisaccharide (Cat#: XCO0060Q) Blood group B trisaccharide (Cat#: XCO0068Q) Blood group H disaccharide (Cat#: XCO0074Q) Lewis A trisaccharide (Cat#: XCO0079Q) 3'-Sulfated lewis A (Cat#: XCO0080Q) Lewis B tetrasaccharide (Cat#: XCO0083Q) Lewis X trisaccharide (Cat#: XCO0085Q) Lewis Y tetrasaccharide (Cat#: XCO0088Q)
Human Milk Oligosaccharides (HMOs)
Lacto-N-biose (Cat#: XCO0089Q) 2'-Fucosyllactose (Cat#: XCO0091Q) 3-Fucosyllactose (Cat#: XCO0092Q) Lactodifucotetraose (Cat#: XCO0093Q) Lacto-N-triose I (Cat#: XCO0094Q) 3'-Sialyllactose sodium salt (Cat#: XCO0096Q) 6'-Sialyllactose sodium salt (Cat#: XCO0098Q) 3'-Sialyl-3-fucosyllactose (Cat#: XCO0100Q)
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