Nucleoside-based Deoxyribonucleoside Production Service

Nucleoside-based Deoxyribonucleoside Production Service

Overview of Deoxynucleosides

Nucleoside monomers include common nucleoside monomers and modified nucleoside monomers. Common nucleoside monomers include deoxyribonucleosides and ribonucleosides. Deoxyribonucleoside (symbol dNr) is a compound formed by connecting a nitrogenous base (guanine, adenine, thymine, cytosine) with a deoxyribose β-glycosidic bond, and forms with purines bicyclic compounds, and pyrimidine to generate monocyclic compounds. Deoxyribonucleosides are then combined with phosphoric acid to generate deoxynucleotides. Deoxynucleosides are structural fragments of DNA that are essential for the development and normal operation of organisms.

Fig.1 DNA and RNA nucleoside composition unit.Fig.1 DNA and RNA nucleoside composition unit. (Seley-Radtke & Yates, 2012)

Nucleoside-based Deoxyribonucleoside Production Service

With the rapid rise of oligonucleotide drugs, as important structural raw materials of oligonucleotide drugs, the market demand for deoxyribonucleoside is also growing rapidly. CD BioGlyco is committed to providing clients with comprehensive custom deoxyribonucleoside production service services with high quality.

  • Production methods
    • Chemical and biosynthetic methods are used to synthesize deoxyribonucleoside.
  • Production capacity
    • At present, CD BioGlyco has made it possible to realize the large-scale production of deoxyribonucleoside.

The series nucleoside-based deoxyribonucleoside production service provided by CD BioGlyco include:

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Nucleoside-based deoxyadenosine production service

CD BioGlyco has extensive experience in nucleoside-based deoxyadenosine production. Welcome clients from worldwide to inquire about our production services.

Nucleoside-based deoxyguanosine production service

CD BioGlyco provides high-quality service to facilitate our clients' nucleoside-based deoxyguanosine production service.

Nucleoside-based thymidine production service

CD BioGlyco owns a team of technical experts to deal with any problem you may meet in nucleoside-based thymidine production service.

Nucleoside-based deoxyuridine production service

CD BioGlyco is proud to offer our clients nucleoside-based deoxyuridine production service with the best quality.

Nucleoside-based deoxycytidine production service

CD BioGlyco is a leader in nucleoside production, providing efficient, accurate, and reproducible nucleoside-based deoxycytidine production service.

Applications

  • Raw materials for the development of molecular diagnostic reagent production
    • Based on the characteristics of deoxynucleosides, it is widely used in the research of synthetic oligonucleotides and genetic engineering. It is an important raw material for genetic medicine and genetic engineering research.
  • Intermediates for antiviral and antitumor drugs
    • Deoxyribonucleoside is a useful intermediate for the chemical synthesis of various antiviral and antitumor drugs.

Advantages

  • Highly pure and environmentally friendly.
  • Our production method avoids a low-yielding reaction and an expensive, proprietary isolation technology, multiple impurities, and complex reactions, which possesses a potential for industrial production.
  • We guarantee product stability and production yield.

CD BioGlyco provides efficient, accurate, and reproducible deoxyribonucleoside products. We have advanced equipment and technologies. If you have Nucleotide Production projects in hand, please feel free to contact us for more information.

Reference

  1. Seley-Radtke, K.L.; Yates, M.K. The evolution of nucleoside analogue antivirals: A review for chemists and non-chemists. Part 1: Early structural modifications to the nucleoside scaffold. Antiviral Research. 2018, 154: 66-86.
This service is for Research Use Only, not intended for any clinical use.

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