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PDGFR inhibitor AB1010, Purity ≥98%
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Cat. No.: X24-06-ZQ133

PDGFR inhibitor AB1010, Purity ≥98%

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Synonym: 790299-79-5; PDGFR inhibitor; AB1010; Masivet

  • MDL: MFCD09954132
  • CAS Number: 790299-79-5
  • Compound CID: 10074640
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
AB1010, soluble in DMSO and ethanol and insoluble in water, blocks the activity of platelet-derived growth factor receptors (PDGFR), which play a crucial role in cell growth, angiogenesis, and tissue. It targets LynB, PDGFRα, Abl1, Akt1, Bmx, BTK, c-Fms, c-Met, c-Ret, EGFR, and Fes.
Molecular Weight
498.6
Molecular Formula
C28H30N6OS
Targets
LynB: 510 nM; PDGFRα: 540 nM; Abl1: 1.20 μM; Akt1: >10 μM; Bmx: >10 μM; BTK: >10 μM; c-Fms; c-Met: >10 μM; c-Ret: >10 μM; EGFR: >10 μM; Fes: >10 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 91 mg/mL (182.49 mM); Water: Insoluble; Ethanol: 4 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
AB1010, or Masitinib, is a PDGFR inhibitor in investigations into cancer therapeutics.
Publications
Publications (0)

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