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PDGFR inhibitor ABT-869, Purity ≥98%
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Cat. No.: X24-06-ZQ132

PDGFR inhibitor ABT-869, Purity ≥98%

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Synonym: 796967-16-3; PDGFR inhibitor; ABT869; ABT-869

  • MDL: MFCD11840918
  • CAS Number: 796967-16-3
  • Compound CID: 11485656
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
ABT-869, soluble in DMSO and insoluble in ethanol and water, blocks the activity of platelet-derived growth factor receptors (PDGFR), which play a crucial role in cell growth, angiogenesis, and tissue. It targets CSF-1R, VEGFR2/KDR, Akt, c-Met, Cdc2, EGFR, FGFR, FGR, FLT3, Fyn, and Hck.
Molecular Weight
375.4
Molecular Formula
C21H18FN5O
Targets
CSF-1R: 3 nM; VEGFR2/KDR: 4 nM; Akt: >50 μM; c-Met: >50 μM; Cdc2: 9.8 μM; EGFR: >50 μM; FGFR: >12.5 μM; FGR: >50 μM; FLT3: 4 nM; Fyn: >50 μM; Hck: >50 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 73 mg/mL (194.45 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
ABT-869 serves as a PDGFR inhibitor in research exploring mechanisms of tumor growth control.
Publications
Publications (0)

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