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PDGFR inhibitor BAY 57-9352, Purity ≥98%

Cat. No.: X24-06-ZQ151

PDGFR inhibitor BAY 57-9352, Purity ≥98%

Synonym: 332012-40-5; PDGFR inhibitor; BAY57-9352

  • MDL: MFCD18251453
  • CAS Number: 332012-40-5
  • Compound CID: 9808844
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
BAY 57-9352, soluble in DMSO and ethanol and insoluble in water, blocks the activity of platelet-derived growth factor receptors (PDGFR), which play a crucial role in cell growth, angiogenesis, and tissue. It targets c-Kit, PDGFRα, VEGFR2, and VEGFR3.
Molecular Weight
409.8
Molecular Formula
C20H16ClN5O3
Targets
c-Kit: 1 nM; PDGFRα: 15 nM; VEGFR2: 6 nM; VEGFR3: 4 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 71 mg/mL (173.24 mM); Water: Insoluble; Ethanol: 1 mg/mL (2.44 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
BAY 57-9352 is used to inhibit PDGFR, providing insights into its role in cancer development and potential therapeutic approaches.
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