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PDGFR inhibitor Imatinib mesylate, Purity ≥98%
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Cat. No.: X24-06-ZQ126

PDGFR inhibitor Imatinib mesylate, Purity ≥98%

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Synonym: 220127-57-1; PDGFR inhibitor; Gleevec; Glivec; CGP-57148B; STI-571

  • MDL: MFCD04307699
  • CAS Number: 220127-57-1
  • Compound CID: 123596
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Product Size
100 mg; 200 mg; 500 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Imatinib mesylate, soluble in DMSO and water and insoluble in ethanol, blocks the activity of platelet-derived growth factor receptors (PDGFR), which play a crucial role in cell growth, angiogenesis, and tissue. It targets c-Kit (M-07e cells), PDGFR, and v-Abl.
Molecular Weight
589.7
Molecular Formula
C29H31N7O.CH4SO3
Targets
c-Kit (M-07e cells): 100 nM; PDGFR: 100 nM; v-Abl: 600 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 101 mg/mL (171.26 mM); Water: 101 mg/mL (171.26 mM); Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Imatinib mesylate is applied as a PDGFR inhibitor in research focused on cancer treatment mechanisms involving PDGFR blockade.
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