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PDGFR inhibitor STI571, Purity ≥98%
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Cat. No.: X24-06-ZQ125

PDGFR inhibitor STI571, Purity ≥98%

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Synonym: 152459-95-5; PDGFR inhibitor; STI571; Glivec

  • MDL: MFCD05662257
  • CAS Number: 152459-95-5
  • Compound CID: 5291
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Product Size
250 mg; 500 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
STI571, soluble in DMSO and insoluble in ethanol and water, blocks the activity of platelet-derived growth factor receptors (PDGFR), which play a crucial role in cell growth, angiogenesis, and tissue. It targets c-Kit (M-07e cells), PDGFR, and v-Abl.
Molecular Weight
493.6
Molecular Formula
C29H31N7O
Targets
c-Kit (M-07e cells): 100 nM; PDGFR: 100 nM; v-Abl: 600 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 28 mg/mL (56.72 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
STI571, known as Imatinib, is a PDGFR inhibitor crucial for research on chronic diseases like leukemia and cancer.
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