Sunitinib malate, soluble in DMSO and insoluble in ethanol and water, blocks the activity of platelet-derived growth factor receptors (PDGFR), which play a crucial role in cell growth, angiogenesis, and tissue. It targets FLT3, PDGFRβ, EGFR, FGFR1, Kit, and VEGFR2.
Sunitinib malate is utilized to study and inhibit PDGFR, which contributes to understanding tumor growth and angiogenesis.
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