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PDGFR inhibitor Sunitinib malate, Purity ≥98%

Cat. No.: X24-06-ZQ149

PDGFR inhibitor Sunitinib malate, Purity ≥98%

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Synonym: 341031-54-7; PDGFR inhibitor; SU-11248

  • MDL: MFCD08282795
  • CAS Number: 341031-54-7
  • Compound CID: 6456015
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Product Size
50 mg; 100 mg; 200 mg; 500 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Sunitinib malate, soluble in DMSO and insoluble in ethanol and water, blocks the activity of platelet-derived growth factor receptors (PDGFR), which play a crucial role in cell growth, angiogenesis, and tissue. It targets FLT3, PDGFRβ, EGFR, FGFR1, Kit, and VEGFR2.
Molecular Weight
532.6
Molecular Formula
C22H27FN4O2.C4H6O5
Targets
FLT3; PDGFRβ: 2 nM; EGFR: >20 μM; FGFR1: 2.9 μM; Kit; VEGFR2: 80 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 13 mg/mL (24.41 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Sunitinib malate is utilized to study and inhibit PDGFR, which contributes to understanding tumor growth and angiogenesis.
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