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PDGFR inhibitor Toceranib phosphate, Purity ≥98%

Cat. No.: X24-06-ZQ153

PDGFR inhibitor Toceranib phosphate, Purity ≥98%

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Synonym: 874819-74-6; PDGFR inhibitor; SU 11654; PHA 291639; SU11654; SU-11654; PHA-291639; PHA291639

  • MDL: MFCD25372034
  • CAS Number: 874819-74-6
  • Compound CID: 16034840
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Product Size
10 mg; 50 mg; 200 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Toceranib phosphate, soluble in DMSO and water and insoluble in ethanol, blocks the activity of platelet-derived growth factor receptors (PDGFR), which play a crucial role in cell growth, angiogenesis, and tissue. It targets Flk-1 and PDGFRβ.
Molecular Weight
494.45
Molecular Formula
C22H28FN4O6P
Targets
Flk-1: 6 nM (Ki); PDGFRβ: 5 nM (Ki)
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 2 mg/mL (4.04 mM); Water: 2 mg/mL (4.04 mM); Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Toceranib phosphate is leveraged as a PDGFR inhibitor in research focused on canine tumors and comparative oncology.
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