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PI3K inhibitor A66, Purity ≥98%
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Cat. No.: X24-05-ZQ066

PI3K inhibitor A66, Purity ≥98%

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Synonym: 1166227-08-2; A-66; PI3K inhibitor

  • CAS Number: 1166227-08-2
  • Compound CID: 42636535
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
A66, soluble in DMSO and ethanol and insoluble in water, is a potent compound that inhibits PI3 kinase activity. It targets p110α, p110α E545K, p110α H1047R, p110γ, PI3K-C2β, and PI3K-C2β.
Molecular Weight
393.53
Molecular Formula
C17H23N5O2S2
Targets
p110α: 32 nM; p110α E545K: 30 nM; p110α H1047R: 43 nM; p110γ: 3480 nM; PI3K-C2β: 462 nM; PI3K-C2β: 236 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 77 mg/mL (195.66 mM); Water: Insoluble; Ethanol: 1 mg/mL (2.54 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
A66 is used in research to study its specific inhibition of the p110α isoform of PI3K, aiding in the understanding of PI3K signaling in cancer and metabolism.
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