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PI3K inhibitor Acalisib, Purity ≥98%
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Cat. No.: X24-05-ZQ067

PI3K inhibitor Acalisib, Purity ≥98%

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Synonym: 870281-34-8; GS-9820; PI3K inhibitor

  • CAS Number: 870281-34-8
  • Compound CID: 11618268
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Product Size
5 mg; 10 mg; 25 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Acalisib, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets DNA-PK, hVps34, PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ.
Molecular Weight
401.4
Molecular Formula
C21H16FN7O
Targets
DNA-PK: 18749 nM; hVps34: 12682 nM; PI3Kα: 5441 nM; PI3Kβ: 3377 nM; PI3Kδ: 12.7 nM; PI3Kγ: 1389 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 76 mg/mL (189.34 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Acalisib is utilized in research for its selective inhibition of PI3K δ, useful in studying B-cell malignancies and autoimmune conditions.
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