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PI3K inhibitor AZD8186, Purity ≥98%
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Cat. No.: X24-05-ZQ076

PI3K inhibitor AZD8186, Purity ≥98%

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Synonym: 1627494-13-6; AZD 8186; AZD-8186; PI3K inhibitor

  • CAS Number: 1627494-13-6
  • Compound CID: 52913813
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Product Size
10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
AZD8186, soluble in warmed DMSO and warmed ethanol and insoluble in water, is a potent compound that inhibits PI3 kinase activity. It targets PI3Kβ, PI3Kδ, PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ.
Molecular Weight
457.47
Molecular Formula
C24H25F2N3O4
Targets
PI3Kβ: 4 nM; PI3Kδ: 12 nM; PI3Kα: 35 nM; PI3Kβ: 3 nM; PI3Kδ: 17 nM; PI3Kγ: 675 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
Warmed DMSO: 82 mg/mL (179.25 mM); Water: Insoluble; Warmed ethanol: 32 mg/mL (69.94 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
AZD8186 is researched for its dual PI3K β and δ inhibitory properties, important in exploring treatment avenues for PTEN-deficient cancers.
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