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PI3K inhibitor AZD8835, Purity ≥98%
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Cat. No.: X24-05-ZQ077

PI3K inhibitor AZD8835, Purity ≥98%

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Synonym: 1620576-64-8; AZD 8835; AZD-8835; PI3K inhibitor

  • CAS Number: 1620576-64-8
  • Compound CID: 76685059
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Product Size
5 mg; 10 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
AZD8835, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets PI3Kα, PI3Kα-E545K, PI3Kα-H1047R, PI3Kβ, PI3Kδ, and PI3Kγ.
Molecular Weight
469.54
Molecular Formula
C22H31N9O3
Targets
PI3Kα: 6.2 nM; PI3Kα-E545K: 6 nM; PI3Kα-H1047R: 5.8 nM; PI3Kβ: 431 nM; PI3Kδ: 5.7 nM; PI3Kγ: 90 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 83 mg/mL (176.76 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
AZD8835 is utilized to understand the dual inhibition of PI3K α and δ, providing insights into its therapeutic potential in cancers with PI3K pathway dysregulation.
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