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PI3K inhibitor BAY 80-6946, Purity ≥98%
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Cat. No.: X24-05-ZQ078

PI3K inhibitor BAY 80-6946, Purity ≥98%

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Synonym: 1032568-63-0; BAY80-6946; BAY806946; Copanlisib; PI3K inhibitor

  • CAS Number: 1032568-63-0
  • Compound CID: 135565596
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
BAY 80-6946, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets mTOR, PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ.
Molecular Weight
480.2
Molecular Formula
C23H28N8O4
Targets
mTOR: 45 nM; PI3Kα: 0.5 nM; PI3Kβ: 3.7 nM; PI3Kδ: 0.7 nM; PI3Kγ: 6.4 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: Insoluble; Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
BAY 80-6946, also known as copanlisib, is studied for its selective inhibition of PI3K α and δ isoforms, relevant for treating hematological malignancies and solid tumors.
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