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PI3K inhibitor GNE 477, Purity ≥98%
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Cat. No.: X24-05-ZQ020

PI3K inhibitor GNE 477, Purity ≥98%

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Synonym: 1032754-81-6; GNE-477; GNE477; PI3K inhibitor

  • CAS Number: 1032754-81-6
  • Compound CID: 25207689
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Product Size
2 mg; 5 mg; 10 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
GNE 477, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets mTOR and PI3Kα.
Molecular Weight
504.64
Molecular Formula
C21H28N8O3S2
Targets
mTOR: 21 nM (Ki); PI3Kα: 4 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 24 mg/mL (47.56 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
GNE 477 can be used to investigate the inhibition of PI3K/mTOR pathways in cancer research.
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