Cat. No.: X24-05-ZQ095
PI3K inhibitor GDC-0941, Purity ≥98%
Synonym: 957054-30-7; GDC0941; Pictilisib; PI3K inhibitor
- CAS Number: 957054-30-7
- Compound CID: 17755052
Product Size
5 mg; 10 mg; 50 mg; 200 mg
Properties
Description
GDC-0941, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets p110β, p110δ, C2β, DNA-PK, mTOR, p110α, p110γ, and Vps34.
Molecular Formula
C23H27N7O3S2
Targets
p110β: 33 nM; p110δ: 3 nM; C2β: 0.67 μM; DNA-PK: 1.23 μM; mTOR: 0.58 μM; p110α: 3 nM; p110γ: 75 nM; Vps34: >10 μM
Solubility
DMSO: 40 mg/mL (77.87 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
GDC-0941 aids in researching the inhibition of all class I PI3K isoforms, specifically in cancer therapy studies.
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