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PI3K inhibitor IPI-145, Purity ≥98%

Cat. No.: X24-05-ZQ105

PI3K inhibitor IPI-145, Purity ≥98%

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Synonym: 1201438-56-3; Duvelisib; IPI145; IPI 145; IPI-145. INK-1197; INK 1197; INK1197; PI3K inhibitor

  • CAS Number: 1201438-56-3
  • Compound CID: 50905713
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
IPI-145, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets PI3Kδ, PI3Kγ, PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ.
Molecular Weight
416.86
Molecular Formula
C22H17ClN6O
Targets
PI3Kδ: 23 pM (Ki); PI3Kγ: 243pM (Ki); PI3Kα: 25900 pM (Ki); PI3Kβ: 1564pM (Ki); PI3Kδ: 23pM (Ki); PI3Kγ: 243pM (Ki)
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 76 mg/mL (182.31 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
IPI-145 is used to evaluate dual inhibition of PI3K-δ and PI3K-γ isoforms, important for researching blood cancers.
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