Cat. No.: X24-05-ZQ110
PI3K inhibitor Leniolisib, Purity ≥98%
Synonym: 1354690-24-6; CDZ-173; CDZ 173; CDZ173; PI3K inhibitor
- CAS Number: 1354690-24-6
- Compound CID: 57495353
Product Size
2 mg; 5 mg; 25 mg
Properties
Description
Leniolisib, soluble in DMSO and ethanol and insoluble in water, is a potent compound that inhibits PI3 kinase activity. It targets DNA-PK, PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ.
Molecular Formula
C21H25F3N6O2
Targets
DNA-PK: 880 nM; PI3Kα: 280 nM; PI3Kβ: 480 nM; PI3Kδ: 11 nM; PI3Kγ: 2.57 nM
Solubility
DMSO: 81 mg/mL (179.81 mM); Water: Insoluble; Ethanol: 12 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
Leniolisib aids in studying the selective PI3Kδ inhibition relevant to immune disorders.
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