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PI3K inhibitor NVP-BKM120 hydrochloride, Purity ≥98%
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Cat. No.: X24-05-ZQ120

PI3K inhibitor NVP-BKM120 hydrochloride, Purity ≥98%

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Synonym: 1312445-63-8; BKM-120 hydrochloride; BKM120 hydrochloride; BKM 120 hydrochloride; PI3K inhibitor

  • CAS Number: 1312445-63-8
  • Compound CID: 66577015
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Product Size
5 mg; 10 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
NVP-BKM120 hydrochloride is a potent compound that inhibits PI3 kinase activity. It targets mTOR, p110α, p110α-E545K, p110α-H1047R, p110β, p110δ, p110γ, and Vps34.
Molecular Weight
446.85
Molecular Formula
C18H21F3N6O2.HCl
Targets
mTOR: 4.6 μM; p110α: 52 μM; p110α-E545K: 4.6 μM; p110α-H1047R: 99 nM; p110β: 166 nM; p110δ: 116 nM; p110γ: 262 μM; Vps34: 2.4 μM
Form
Lyophilized powder
Purity
≥98%
Identity
Confirmed by NMR/HPLC/MS.
Applications
NVP-BKM120 hydrochloride targets PI3K for studying cancer cell proliferation and survival.
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