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PI3K inhibitor PF-4989216, Purity ≥98%
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Cat. No.: X24-05-ZQ127

PI3K inhibitor PF-4989216, Purity ≥98%

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Synonym: 1276553-09-3; PF4989216; PF 4989216; PI3K inhibitor

  • CAS Number: 1276553-09-3
  • Compound CID: 51033720
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Product Size
5 mg; 10 mg; 25 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
PF-4989216, soluble in DMSO and warmed ethanol and insoluble in water, is a potent compound that inhibits PI3 kinase activity. It targets p110α, p110β, p110δ, p110γ, and Vps34.
Molecular Weight
380.4
Molecular Formula
C18H13FN6OS
Targets
p110α: 2 nM; p110β: 142 nM; p110δ: 1 nM; p110γ: 65 nM; Vps34: 110 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 66 mg/mL (173.49 mM); Water: Insoluble; Warmed ethanol: 6 mg/mL (15.77 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
PF-4989216 is utilized to investigate PI3Kγ signaling in cancer and inflammation.
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