Cat. No.: X24-05-ZQ147
PI3K inhibitor PIK-III, Purity ≥98%
Synonym: 1383716-40-2; VPS34-IN2; PI3K inhibitor
- CAS Number: 1383716-40-2
- Compound CID: 67983123
Product Size
5 mg; 10 mg; 25 mg
Properties
Description
PIK-III, soluble in DMSO and ethanol and insoluble in water, is a potent compound that inhibits PI3 kinase activity. It targets PI3Kδ, PI3Kγ, mTOR, PI3Kα, PI3Kβ, PI3Kβ, and Vps34.
Molecular Formula
C17H17N7
Targets
PI3Kδ: 1.2 μM; PI3Kγ: 3.04 μM; mTOR: >9.1 μM; PI3Kα: 3.96 μM; PI3Kβ: >9.1 μM; PI3Kβ: 4.43 μM; Vps34: 0.018 μM
Solubility
DMSO: 56 mg/mL (175.34 mM); Water: Insoluble; Ethanol: 56 mg/mL (175.34 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
PIK-III serves as an inhibitor of autophagic PI3K VPS34, useful for studying autophagy and cellular trafficking.
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