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PI3K inhibitor PKI-402, Purity ≥98%
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Cat. No.: X24-05-ZQ148

PI3K inhibitor PKI-402, Purity ≥98%

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Synonym: 1173204-81-3; PKI402; PI3K inhibitor

  • CAS Number: 1173204-81-3
  • Compound CID: 44187953
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
PKI-402, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets mTOR, PI3Kα, PI3Kα-E545K, PI3Kα-H1047R, PI3Kβ, PI3Kδ, and PI3Kγ.
Molecular Weight
570.7
Molecular Formula
C29H34N10O3
Targets
mTOR: 3 nM; PI3Kα: 2 nM; PI3Kα-E545K: 3 nM; PI3Kα-H1047R: 3 nM; PI3Kβ: 7 nM; PI3Kδ: 14 nM; PI3Kγ: 16 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 0.35 mg/mL (0.61 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
PKI-402 is utilized to investigate the dual inhibition of PI3K and mTOR pathways and their potential therapeutic applications in cancer.
Publications
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