Cat. No.: X24-05-ZQ154
PI3K inhibitor Rigosertib sodium, Purity ≥98%
Synonym: 592542-60-4; ON-01910 sodium; ON01910; ON 01910; PI3K inhibitor
- CAS Number: 592542-60-4
- Compound CID: 23696523
Product Size
5 mg; 10 mg; 50 mg; 100 mg
Properties
Description
Rigosertib sodium is a potent compound that inhibits PI3 kinase activity. It targets BCR-ABL, Cdk1, Flt1, Fyn, PDGFR, PLK1, PLK2, and Src.
Molecular Formula
C21H24NNaO8S
Targets
BCR-ABL: 32 nM; Cdk1: 260 nM; Flt1: 42 nM; Fyn: 182 nM; PDGFR: 18 nM; PLK1: 9 nM; PLK2: 260 nM; Src: 155 nM
Identity
Confirmed by NMR/HPLC/MS.
Applications
Rigosertib sodium is used to study its inhibition of PI3K and its potential anti-cancer effects, especially in myelodysplastic syndromes.
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