Cat. No.: X24-05-ZQ174
PI3K inhibitor XL-147, Purity ≥98%
Synonym: 934526-89-3; SAR245408; XL 147; XL147; SAR-245408; SAR 245408; Pilaralisib; PI3K inhibitor
- CAS Number: 934526-89-3
- Compound CID: 56599306
Product Size
5 mg; 10 mg; 25 mg
Properties
Description
XL-147, soluble in warmed DMSO and insoluble in water and ethanol, is a potent compound that inhibits PI3 kinase activity. It targets PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ.
Molecular Formula
C25H25ClN6O4S
Targets
PI3Kα: 39 nM; PI3Kβ: 36 nM; PI3Kδ: 36 nM; PI3Kγ: 23 nM
Solubility
Warmed DMSO: 92 mg/mL (170.04 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
XL-147 is utilized to understand the inhibition of PI3K and its downstream effects in cancer therapeutics.
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