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PKC inhibitor Sotrastaurin, Purity ≥98%
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Cat. No.: X23-10-ZQ818

PKC inhibitor Sotrastaurin, Purity ≥98%

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Synonym: Sotrastaurin; 425637-18-9; AEB071; Sotrastaurin (AEB071); AEB-071; 3-(1H-Indol-3-yl)-4-(2-(4-methylpiperazin-1-yl)quinazolin-4-yl)-1H-pyrrole-2,5-dione; 3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione; PKC inhibitor

  • CAS Number: 425637-18-9
  • Compound CID: 10296883
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Sotrastaurin, soluble in DMSO and ethanol and insoluble in water, acts as an ATP-competitive PKC inhibitor. It targets PKCα, PKCβ1, PKCδ, PKCε, PKCη, and PKCθ.
Molecular Weight
438.5
Molecular Formula
C25H22N6O2
Targets
PKCα: 0.95 nM (Ki); PKCβ1: 0.64 nM (Ki); PKCδ: 2.1 nM (Ki); PKCε: 3.2 nM (Ki); PKCη: 1.8 nM (Ki); PKCθ: 0.22 nM (Ki)
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 79 mg/mL (180.17 mM); Water: Insoluble; Ethanol: 2 mg/mL (4.56 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Sotrastaurin can be used to study the inhibition of protein kinase C (PKC) in various cellular signaling pathways.
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