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Ripasudil
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Cat. No.: X23-12-YM033

Ripasudil

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Synonym: 887375-67-9; Ripasudil hydrochloride dihydrate; Glanatec

  • CAS Number: 887375-67-9
  • PubChem CID: 11625386
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Ripasudil, soluble in DMSO, ethanol and water, selectively inhibits the phosphorylation activity of ROCK, which is involved in various cellular processes. It targets ROCK1, and ROCK2.
Molecular Weight
395.88
Molecular Formula
C15H23ClFN3O4S
Targets
ROCK1: 51 nM; ROCK2: 19 nM
Form
Lyophilized powder
Purity
>98%
Solubility
DMSO: 25 mg/mL (63.14 mM); Water: 76 mg/mL (191.97 mM); Ethanol: 5 mg/mL (12.63 mM)
Applications
Ripasudil can be used in the study of corneal endothelial dysfunction, a condition characterized by a decrease in the number or function of endothelial cells in the cornea.
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