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ROCK inhibitor AT13148, Purity ≥98%
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Cat. No.: X24-05-ZQ850

ROCK inhibitor AT13148, Purity ≥98%

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Synonym: 1056901-62-2; AT 13148; AT-13148; ROCK inhibitor

  • CAS Number: 1056901-62-2
  • Compound CID: 24905401
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Product Size
5 mg; 10 mg; 25 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
AT13148, soluble in DMSO and insoluble in ethanol and water, blocks the ATP-binding site of ROCK, thereby inhibiting its kinase activity. It targets ROCK1, ROCK2, Akt1, and Akt2.
Molecular Weight
313.78
Molecular Formula
C17H16ClN3O
Targets
ROCK1: 6 nM; ROCK2: 4 nM; Akt1: 38 nM; Akt2: 402 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 55 mg/mL (175.28 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
AT13148 is used to examine its role as a multi-AGC kinase inhibitor in cancer research.
Publications
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