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Y-27632
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Cat. No.: X23-12-YM062

Y-27632

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Synonym: 146986-50-7; Y-27632 Dihydrochloride

  • CAS Number: 146986-50-7
  • PubChem CID: 448042
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Y-27632 selectively inhibits the phosphorylation activity of ROCK, which is involved in various cellular processes. It targets Citron kinase, PKA, PKCα, PKN, ROCK-I, and ROCK-II.
Molecular Weight
247.34
Molecular Formula
C14H21N3O
Targets
Citron kinase: 5.3 μM; PKA: 25 μM; PKCα: 73 μM; PKN: 3.1 μM; ROCK-I: 220 nM; ROCK-II: 300 nM
Form
Lyophilized powder
Purity
>98%
Applications
Y-27632 can be used for its neuroprotective effects by reducing neuronal apoptosis, inflammation, and oxidative stress.
Publications
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