Properties
                                        
                            Description
                            Glycyl-H 1152 2HCl blocks the ATP-binding site of ROCK, thereby inhibiting its kinase activity. It targets Aurora A, CaMK II, PKG, and ROCKII.
                         
                                                                            
                                                            
                            Molecular Formula
                            C18H24N4O3S.2HCl
                         
                                                                                                                                            
                            Targets
                            Aurora A: 2.35 μM; CaMK II: 2.57 μM; PKG: 3.26 μM; ROCKII: 11.8 nM
                         
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
                                                            
                                                                                                                                                                                            
                            Identity
                            Confirmed by NMR/HPLC/MS.
                         
                                                                                                                                                            
                            Applications
                            Glycyl-H 1152 2HCl is used to study the inhibition of Rho-associated protein kinases in cell motility research.