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ROCK inhibitor GSK429286A, Purity ≥98%
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Cat. No.: X23-10-ZQ801

ROCK inhibitor GSK429286A, Purity ≥98%

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Synonym: GSK429286A; 864082-47-3; RHO-15; N-(6-Fluoro-1H-indazol-5-yl)-6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1H-pyridine-5-carboxamide; N-(6-fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-4-(4-(trifluoromethyl)phenyl)-1,4,5,6-tetrahydropyridine-3-carboxamide; ROCK inhibitor

  • MDL: MFCD16618404
  • CAS Number: 864082-47-3
  • Compound CID: 11373846
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
GSK429286A, soluble in DMSO and ethanol and insoluble in water, blocks the ATP-binding site of ROCK, thereby inhibiting its kinase activity. It targets ROCK1 and ROCK2.
Molecular Weight
432.4
Molecular Formula
C21H16F4N4O2
Targets
ROCK1: 14 nM; ROCK2: 63 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 81 mg/mL (187.33 mM); Water: Insoluble; Ethanol: 4 mg/mL (9.25 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
GSK429286A can be used to investigate its inhibitory effects on Rho kinase and its implications in treating cardiovascular and fibrotic diseases.
Publications
Publications (0)

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