Properties
                                        
                            Description
                            H-1152 blocks the ATP-binding site of ROCK, thereby inhibiting its kinase activity. It targets Abl, AMPK, AuroraA, and CaMKII.
                         
                                                                            
                                                            
                            Molecular Formula
                            C16H21N3O2S
                         
                                                                                                                                            
                            Targets
                            Abl: 7.77 μM; AMPK: 100 μM; AuroraA: 0.745 μM; CaMKII: 0.18 μM
                         
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
                                                            
                                                                                                                                                                                            
                            Identity
                            Confirmed by NMR/HPLC/MS.
                         
                                                                                                                                                            
                            Applications
                            H-1152 is utilized to study its inhibitory effects on Rho-kinase in cellular contractility research.