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ROCK inhibitor RKI-1447, Purity ≥98%
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Cat. No.: X24-05-ZQ852

ROCK inhibitor RKI-1447, Purity ≥98%

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Synonym: 1342278-01-6; RKI1447; RKI 1447. ROCK inhibitor XIII; ROCK inhibitor

  • CAS Number: 1342278-01-6
  • Compound CID: 60138149
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
RKI-1447, soluble in DMSO and insoluble in ethanol and water, blocks the ATP-binding site of ROCK, thereby inhibiting its kinase activity. It targets ROCK1 and ROCK2.
Molecular Weight
326.37
Molecular Formula
C16H14N4O2S
Targets
ROCK1: 14.5 nM; ROCK2: 6.2 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 62 mg/mL (189.97 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
RKI-1447 is utilized to investigate its inhibitory effects on ROCK1 and ROCK2 in the study of cell migration and invasion.
Publications
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