Cat. No.: X24-05-ZQ862
ROCK inhibitor SLx-2119, Purity ≥98%
Synonym: 911417-87-3; SLx 2119; SLx2119; ROCK inhibitor; KD-025; KD025; ROCK inhibitor
- CAS Number: 911417-87-3
- Compound CID: 11950170
Product Size
5 mg; 10 mg; 100 mg
Properties
Description
SLx-2119, soluble in DMSO and insoluble in ethanol and water, blocks the ATP-binding site of ROCK, thereby inhibiting its kinase activity. It targets ROCK2 and ROCK2.
Molecular Formula
C26H24N6O2
Targets
ROCK2: 60 nM; ROCK2: 41 nM (Ki)
Solubility
DMSO: 84 mg/mL (185.63 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
SLx-2119 can be used to study the inhibition of ROCK2 for potential therapeutic effects in fibrosis and inflammation.
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