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ROCK inhibitor Y-33075 dihydrochloride, Purity ≥98%
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Cat. No.: X23-10-ZQ820

ROCK inhibitor Y-33075 dihydrochloride, Purity ≥98%

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Synonym: 173897-44-4; Y-33075 dihydrochloride; Y-39983 dihydrochloride; (R)-4-(1-Aminoethyl)-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)benzamide dihydrochloride; Y-33075 (dihydrochloride); 4-[(1R)-1-Aminoethyl]-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)benzamide; ROCK inhibitor

  • CAS Number: 173897-44-4
  • Compound CID: 20601328
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Product Size
250 mg; 500 mg; 1000 mg; 2000 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Y-33075 dihydrochloride, soluble in DMSO, water and ethanol, blocks the ATP-binding site of ROCK, thereby inhibiting its kinase activity. It targets CaMKII, PKC, and ROCK.
Molecular Weight
353.25
Molecular Formula
C16H18Cl2N4O
Targets
CaMKII: 810 nM; PKC: 420 nM; ROCK: 3.6 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 60 mg/mL (169.85 mM); Water: 60 mg/mL (169.85 mM); Ethanol: 2 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
Y-33075 dihydrochloride can be used for studying the effects of Rho-associated protein kinase (ROCK) inhibition in a variety of cellular processes, such as smooth muscle contraction and cell migration.
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