Cat. No.: X23-10-ZQ819
ROCK inhibitor Y-33075, Purity ≥98%
Synonym: 199433-58-4; Y-33075; Y-39983; Y-39983 free base; Benzamide, 4-(1-aminoethyl)-N-1H-pyrrolo(2,3-b)pyridin-4-yl-, (R)-; Y 39983; 00ALI1GAY2; ROCK inhibitor
- CAS Number: 199433-58-4
- Compound CID: 9810884
Product Size
10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
Y-33075 blocks the ATP-binding site of ROCK, thereby inhibiting its kinase activity. It targets CaMKII, PKC, and ROCK.
Molecular Formula
C16H16N4O
Targets
CaMKII: 810 nM; PKC: 420 nM; ROCK: 3.6 nM
Identity
Confirmed by NMR/HPLC/MS.
Applications
Y-33075 can be used to investigate the inhibition of Rho-associated protein kinase (ROCK), which plays a role in cytoskeleton organization and cell motility.
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