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Sirtuins inhibitor Sirtinol, Purity ≥98%
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Cat. No.: X24-05-ZQ355

Sirtuins inhibitor Sirtinol, Purity ≥98%

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Synonym: 410536-97-9; Sir two inhibitor naphthol; Sirtuins inhibitor

  • CAS Number: 410536-97-9
  • Compound CID: 2827646
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Product Size
10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Sirtinol, soluble in DMSO and insoluble in ethanol and water, is a compound that blocks the activity of sirtuins, a family of NAD+-dependent deacetylases involved in the regulation of aging, metabolism, and stress resistance. It targets hSIRT1, hSIRT2, and ySir2.
Molecular Weight
394.47
Molecular Formula
C26H22N2O2
Targets
hSIRT1: 131 μM; hSIRT2: 57.7 μM; ySir2: 48 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 20 mg/mL (50.7 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Sirtinol is applied to study the inhibition of SIRT1 and SIRT2 and their role in cellular aging and cancer.
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