Cat. No.: X24-06-ZQ379
Trk receptor inhibitor 7,8-Dihydroxyflavone, Purity ≥98%
Synonym: 38183-03-8; Trk receptor inhibitor; 7,8-DHF
- MDL: MFCD00006836
- CAS Number: 38183-03-8
- Compound CID: 1880
Product Size
5 mg; 25 mg; 50 mg; 100 mg
Properties
Description
7,8-Dihydroxyflavone, soluble in DMSO and ethanol and insoluble in water, blocks the activity of tropomyosin receptor kinases, which are involved in the growth and survival of neurons. It targets TrkB receptor.
Molecular Formula
C15H10O4
Targets
TrkB receptor: 320 nM (Kd)
Solubility
DMSO: 44 mg/mL (173.06 mM); Water: Insoluble; Ethanol: 1 mg/mL (3.93 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
7,8-Dihydroxyflavone is used to mimic BDNF activity, offering a research pathway for neuroprotection and therapeutic applications in neurodegenerative diseases.
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