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Trk receptor inhibitor LOXO-101, Purity ≥98%
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Cat. No.: X24-06-ZQ378

Trk receptor inhibitor LOXO-101, Purity ≥98%

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Synonym: 1223403-58-4; Trk receptor inhibitor; LOXO 101; LOXO101; ARRY470; ARRY 470

  • MDL: MFCD28902192
  • CAS Number: 1223403-58-4
  • Compound CID: 46188928
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Product Size
5 mg; 10 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
LOXO-101, soluble in DMSO and ethanol and insoluble in water, blocks the activity of tropomyosin receptor kinases, which are involved in the growth and survival of neurons. It targets TrkA, TrkC, and TrkB.
Molecular Weight
428.44
Molecular Formula
C21H22F2N6O2
Targets
TrkA; TrkC; TrkB
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 85 mg/mL (198.39 mM); Water: Insoluble; Ethanol: 85 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
LOXO-101 is utilized to target and inhibit TRK fusion proteins in research, significant for studying certain types of cancer treatments.
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