GW 441756, soluble in DMSO and insoluble in ethanol and water, blocks the activity of tropomyosin receptor kinases, which are involved in the growth and survival of neurons. It targets C-Raf-1, CDK2, and TrkA.
GW 441756 is used to block Trk receptor activity, which can aid in the research of therapies for pain and neurodegenerative diseases.
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