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Trk receptor inhibitor GW 441756, Purity ≥98%

Cat. No.: X24-06-ZQ380

Trk receptor inhibitor GW 441756, Purity ≥98%

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Synonym: 504433-23-2; Trk receptor inhibitor; GW-441756; GW441756

  • CAS Number: 504433-23-2
  • Compound CID: 9943465
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Product Size
10 mg; 50 mg; 100 mg; 200 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
GW 441756, soluble in DMSO and insoluble in ethanol and water, blocks the activity of tropomyosin receptor kinases, which are involved in the growth and survival of neurons. It targets C-Raf-1, CDK2, and TrkA.
Molecular Weight
275.31
Molecular Formula
C17H13N3O
Targets
C-Raf-1: >12 μM; CDK2: >7 μM; TrkA: 2 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 25 mg/mL (90.81 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
GW 441756 is used to block Trk receptor activity, which can aid in the research of therapies for pain and neurodegenerative diseases.
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