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VEGFR inhibitor AMG706, Purity ≥98%
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Cat. No.: X24-06-ZQ246

VEGFR inhibitor AMG706, Purity ≥98%

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Synonym: 453562-69-1; VEGFR inhibitor; AMG 706; AMG-706

  • MDL: MFCD10567689
  • CAS Number: 453562-69-1
  • Compound CID: 11667893
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
AMG706, soluble in DMSO and ethanol and insoluble in water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against VEGFR. It targets VEGFR1, VEGFR2, and VEGFR3.
Molecular Weight
373.45
Molecular Formula
C22H23N5O
Targets
VEGFR1: 2 nM; VEGFR2: 3 nM; VEGFR3: 6 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 68 mg/mL (182.09 mM); Water: Insoluble; Ethanol: 7 mg/mL (18.74 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
AMG706 serves dual roles as both PDGFR and VEGFR inhibitor, relevant in studies targeting angiogenesis and stromal support in cancers.
Publications
Publications (0)

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