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VEGFR inhibitor AZD2171, Purity ≥98%
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Cat. No.: X24-06-ZQ237

VEGFR inhibitor AZD2171, Purity ≥98%

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Synonym: 288383-20-0; VEGFR inhibitor; Recentin

  • MDL: MFCD09954115
  • CAS Number: 288383-20-0
  • Compound CID: 9933475
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
AZD2171, soluble in DMSO and insoluble in ethanol and water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against VEGFR. It targets c-Kit, VEGFR3/FLT4, Abl, Aurora A, AuroraB, CDK2, CDK4, CSF-1R, EGFR, and FGFR1.
Molecular Weight
450.5
Molecular Formula
C25H27FN4O3
Targets
c-Kit: 2 nM; VEGFR3/FLT4: ≤3 nM; Abl: 260 nM; AuroraA: >10 μM; AuroraB: >10 μM; CDK2: >1 μM; CDK4: >1 μM; CSF-1R: 110 nM; EGFR: 1.6 nM; FGFR1: 26 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 80 mg/mL (177.57 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
AZD2171 inhibits VEGFR, supporting its use in researching anti-angiogenic strategies in oncology.
Publications
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