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VEGFR inhibitor E7080, Purity ≥98%

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Cat. No.: X24-06-ZQ240

VEGFR inhibitor E7080, Purity ≥98%

Synonym: 417716-92-8; VEGFR inhibitor; E-7080

MDL: MFCD16038644
CAS Number: 417716-92-8
Compound CID: 9823820

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

MSDS

Properties

Description

E7080, soluble in warmed DMSO and insoluble in water and ethanol, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against VEGFR. It targets VEGFR1/FLT1, VEGFR3/FLT4, Akt1, CDK4/CyclinD, EphB4, FAK, FGFR1, IGF-1R, Insulin receptor, Kit, and PDGFRα.

Molecular Weight

426.9

Molecular Formula

C₂₁H₁₉ClN₄O₄

Targets

VEGFR1/FLT1: 22 nM; VEGFR3/FLT4: 5.2 nM; Akt1: >10 μM; CDK4/CyclinD: >10 μM; EphB4: >10 μM; FAK: >10 μM; FGFR1: 46 nM; IGF-1R: >10 μM; Insulin receptor: >10 μM; Kit: 100 μM; PDGFRα: 51 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 35 mg/mL (81.99 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

E7080 (also known as Lenvatinib) targets multiple kinases including VEGFR, used in exploring multi-targeted oncology treatments.

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Publications (0)

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