VEGFR inhibitor Fruquintinib, Purity ≥98%

Synonym: 1194506-26-7; VEGFR inhibitor; HMPL-013; HMPL 013; HMPL013

CAS Number: 1194506-26-7
Compound CID: 44480399

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

Fruquintinib, soluble in DMSO and insoluble in ethanol and water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against VEGFR. It targets VEGFR1, VEGFR2, and VEGFR3.

Molecular Weight

393.3927

Molecular Formula

C₂₁H₁₉N₃O₅

Targets

VEGFR1: 33 nM; VEGFR2: 35 nM; VEGFR3: 0.5 nM

Form

Lyophilized powder

Purity

Solubility

DMSO: 6 mg/mL (15.25 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Fruquintinib is used for VEGFR inhibition, advancing research in limiting tumor-induced neovascularization.