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VEGFR inhibitor MGCD-265, Purity ≥98%
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Cat. No.: X24-06-ZQ216

VEGFR inhibitor MGCD-265, Purity ≥98%

Synonym: 875337-44-3; VEGFR inhibitor; MGCD265

  • MDL: MFCD17779287
  • CAS Number: 875337-44-3
  • Compound CID: 24901704
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
MSDS
Properties
Description
MGCD-265, soluble in DMSO and insoluble in ethanol and water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against VEGFR. It targets RON, VEGFR1, MET, Tie-2, VEGFR2, and VEGFR3.
Molecular Weight
517.6
Molecular Formula
C26H20FN5O2S2
Targets
RON: 2 nM; VEGFR1: 3 nM; MET: 1 nM; Tie-2: 7 nM; VEGFR2: 3 nM; VEGFR3: 4 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 99 mg/mL (191.26 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
MGCD-265 functions as a VEGFR inhibitor, contributing to studies aimed at hindering angiogenesis in tumors.
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