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VEGFR inhibitor NVP-BAW2881, Purity ≥98%

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Cat. No.: X24-06-ZQ249

VEGFR inhibitor NVP-BAW2881, Purity ≥98%

Synonym: 861875-60-7; VEGFR inhibitor; BAW2881; BAW-2881; BAW 2881; NVP-BAW-2881; NVP-BAW 2881

MDL: MFCD30343850
CAS Number: 861875-60-7
Compound CID: 16004702

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

NVP-BAW2881, soluble in DMSO and ethanol and insoluble in water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against VEGFR. It targets C-Raf-1, hVEGFR2, B-RAFV599E, c-Abl, c-KIT, hVEGFR1, hVEGFR3, mVEGF2, RET, and TIE-2.

Molecular Weight

424.1147

Molecular Formula

C₂₂H₁₅F₃N₄O₂

Targets

C-Raf-1: 24 nM; hVEGFR2: 9 nM; B-RAFV599E: 76 nM; c-Abl: 99 nM; c-KIT: 2.5 nM; hVEGFR1: 820 nM; hVEGFR3: 420 nM; mVEGF2: 165 nM; RET: 410 nM; TIE-2

Form

Lyophilized powder

Purity

Solubility

DMSO: 76 mg/mL (179.08 mM); Water: Insoluble; Ethanol: 18 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

VEGFR inhibitor NVP-BAW2881 is utilized in research focused on blocking angiogenesis via VEGFR pathways, contributing to cancer therapy studies.

Publications

Publications (0)

Publications

Publications

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